The 3,4-catechol derivative of propranolol, a minor dihydroxylated metabolite

DOI: 10.1021/jm00373a008

Source and publish data:

Journal of Medicinal Chemistry p. 857 - 861 (1984)

Update date:2022-08-05

Topics:

Authors:

Nelson Nelson

Bartels Bartels

Bednarski

Zhang Zhang

Messick Messick

Horng Horng

Ruffolo Jr.

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Article abstract of DOI:10.1021/jm00373a008

The O,O-dibenzyl ether of the 3,4-catechol derivative of propranolol (11) was prepared to determine whether the catechol is a product of metabolic hydroxylation. 4-(Allyloxy)-1,2-naphthoquinone was reduced with sodium dithionite and alkylated with benzyl

Full text of DOI:10.1021/jm00373a008

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