The 3,4-catechol derivative of propranolol, a minor dihydroxylated metabolite

DOI: 10.1021/jm00373a008

Source and publish data:

Journal of Medicinal Chemistry p. 857 - 861 (1984)

Update date:2022-08-05

Topics:

Authors:

Nelson Nelson

Bartels Bartels

Bednarski

Zhang Zhang

Messick Messick

Horng Horng

Ruffolo Jr.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00373a008

The O,O-dibenzyl ether of the 3,4-catechol derivative of propranolol (11) was prepared to determine whether the catechol is a product of metabolic hydroxylation. 4-(Allyloxy)-1,2-naphthoquinone was reduced with sodium dithionite and alkylated with benzyl

Full text of DOI:10.1021/jm00373a008

Products guided by the article

Product name:Naphthalene, 1,2-bis(phenylmethoxy)-4-(2-propenyloxy)-

Cas No:89710-75-8

R&D Labs maybe for 89710-75-8

Zhenjiang Haitong Chemical Industry Co., Ltd.

Contact:+86 (511) 8448-0369

Address:Baoyan Town, Dantu District, Zhenjiang City, Jiangsu, China
zonk drug r&d limited

Contact:+86-20-32051076

Address:1105,Building A, International Business Incubator,Science City
Simagchem Corporation

website:http://www.simagchem.com

Contact:+86-592-2680277

Address:21/F Hualong Office Building,No.6 Hubin East Road, Xiamen,China
Beijing Pure Chem Co.,Ltd.

Contact:+86-10-83993285

Address:Rm.1708, Haobai Tower, Building 6, No.50, North Road, West Third Ring, Haidian District, Beijing, China
Shandong united-rising pharmaceutical cooperation.,ltd.

Contact:008653187965009

Address:171No., Jing5 Road, Shizhong District, Jinan, China

Relevant to this article

Synthesis and configurational assignment of the amino alcohol in the eastern fragment of the GE2270 antibiotics by regio- and stereoselective addition of 2-metalated 4-bromothiazoles to α-chiral electrophiles

Doi:10.1021/jo060462g
(2006)
3-&β-D-ERYTHROFURANOSYL-6,7-DIMETHYL-1-p-TOLYL- AND -1-(p-CHLOROPHENYL-PYRAZOLO(3,4-b)QUINOXALINE C-NUCLEOSIDE ANALOGS

Doi:10.1016/0008-6215(84)85144-7
(1984)
In vivo antihyperlipidemic activity of a new series of N-(Benzoylphenyl) and N-(Acetylphenyl)-1-benzofuran-2-carboxamides in rats

Doi:10.1002/ardp.201100225
(2012)
DNA oxidative damage by terpene catechols as analogues of natural terpene quinone methide precursors in the presence of Cu(II) and/or NADH

Doi:10.1021/tx060021s
(2006)
Reductive coupling of aromatic dialkyl acetals using the combination of zinc and chlorotrimethylsilane in the presence of potassium carbonate

Doi:10.1246/cl.2007.1418
(2007)
N-Glycoside neoglycotrimers from 2,3,4,6-tetra-O-acetyl-β-d-glucopyranosyl azide

Doi:10.1016/j.carres.2006.04.011
(2006)

Article Doi