Synthesis of (Z)- and (E)-6-Hydroxyketamine

DOI: 10.1021/jo00192a011

Source and publish data:

Journal of Organic Chemistry p. 3305 - 3310 (1984)

Update date:2022-08-03

Topics: Synthesis Chemical reactions Compound Isomers Spatial arrangement

Authors:

Woolf, Thomas

Trevor, Anthony

Baillie, Thomas

Castagnoli, Neal

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Article abstract of DOI:10.1021/jo00192a011

(Z)- and (E)-6-hydroxyketamine, potential metabolites of the dissociative anesthetic agent ketamine <(+/-)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone>, have been prepared by oxidation of the trimethylsilyl enol ether of N-(methoxycarbonyl)ketamine wi

Full text of DOI:10.1021/jo00192a011

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