Optimization of novel oxidative DIMs as Nur77 modulators of the Nur77-Bcl-2 apoptotic pathway

DOI: 10.1016/j.ejmech.2020.113020

Source and publish data:

European Journal of Medicinal Chemistry (2021)

Update date:2022-08-04

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Authors:

Tu, Xuhuang

Chen, Xiaohui

Zhang, Dongliang

Gao, Meichun

Liang, Jingmei

Bao, Guoliang

Zhang, Jie

Peng, Shuangzhou

Zhang, Xiaokun

Zeng, Zhiping

Su, Ying

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Article abstract of DOI:10.1016/j.ejmech.2020.113020

Nur77, an orphan nuclear receptor, is a member of the nuclear receptor superfamily. Nur77 plays important roles in various biological processes. Previously we reported that BI1071(DIM-C-pPhCF₃⁺MeSO₃^-), an oxidiz

Full text of DOI:10.1016/j.ejmech.2020.113020

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