Journal of Organic Chemistry p. 10012 - 10023 (2019)
Update date:2022-07-30
Topics:
Cho, Yang Yil
Jang, Hyu Jeong
Kim, Dong Hwan
Kim, Nam Yong
Kim, Nam-Jung
Kim, Young Min
Lee, Soo Jin
Lee, Yong Sup
Park, Boyoung Y.
Son, Seung Hwan
Yoo, Hyung-Seok
A total of 47 flavanones were expediently synthesized via one-pot β-arylation of chromanones, a class of simple ketones possessing chemically unactivated β sites, with arylboronic acids via tandem palladium(II) catalysis. This reaction provides a novel route to various flavanones, including natural products such as naringenin trimethyl ether, in yields up to 92percent.
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