A convenient synthesis of 4,5-bis(trifluoromethyl)pyridazines

DOI: 10.3987/COM-98-8301

Source and publish data:

Heterocycles p. 2221 - 2224 (1998)

Update date:2022-07-29

Topics:

Authors:

Kamitori, Yasuhiro

Hojo, Masaru

Yoshioka, Tatsuya

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Article abstract of DOI:10.3987/COM-98-8301

Acid catalyzed selfcondensation of 3-hydrazono-1,1,1 trifluoroalkan-2-ones (2) prepared from 1,1,1-trifIuoroalkan-2,3-diones (1) and 100% hydrazine hydrate afforded 4,5-bis(trifluoromethyl)pyridazines (3) in satisfactory yields.

Full text of DOI:10.3987/COM-98-8301

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Product name:1-(4-chloro-phenyl)-3,3,3-trifluoro-2,2-dihydroxy-propan-1-one

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