Synthesis and antitumor activity of 9-[(carbamoyloxy)alkyl]anthracyclines: A novel class of anthracycline derivatives

DOI: 10.1021/jm00171a011

Source and publish data:

Journal of Medicinal Chemistry p. 2380 - 2384 (1990)

Update date:2022-08-05

Topics:

Authors:

Adams Adams

Blake Blake

Broadhurst

Bushnell

Hassall Hassall

Hartmann

Keech Keech

Stratton

Thomas Thomas

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Article abstract of DOI:10.1021/jm00171a011

a number of 4-demethoxyanthracyclines having hydroxylalkyl functions at the 9-position have previously been synthesized and shown to have potent antitumor activity. A series of carbamate derivatives of these (hydroxyalkyl)anthracyclines have now been prep

Full text of DOI:10.1021/jm00171a011

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Article Doi

Synthesis and antitumor activity of 9-[(carbamoyloxy)alkyl]anthracyclines: A novel class of anthracycline derivatives

DOI: 10.1021/jm00171a011

Source and publish data:

Authors:

Article abstract of DOI:10.1021/jm00171a011

Full text of DOI:10.1021/jm00171a011

Products guided by the article

R&D Labs maybe for 91577-18-3

Relevant to this article

Nucleophilic Aromatic Substitution in the Pyrrole Ring: Leaving Group Effect

Organotin(IV) complexes of thiohydrazides and thiodiamines: synthesis, spectral and thermal studies

A concise and enantioselective approach to the total synthesis of (-)-lasubine I

A biocompatible surfactant with folded hydrophilic head group: Enhancing the stability of self-inclusion complexes of ferrocenyl in a β-cyclodextrin unit by bond rigidity

A Simple Preparation of Anhydrous Trifluoromethanesulfinate (Triflinate) Salts and Synthesis of Trifluoromethyl Sulfones (Triflones)

Tandem ring expansion of alkenyl benzocyclobutenol derivatives into substituted naphthols