Synthesis and antitumor activity of 9-[(carbamoyloxy)alkyl]anthracyclines: A novel class of anthracycline derivatives

DOI: 10.1021/jm00171a011

Source and publish data:

Journal of Medicinal Chemistry p. 2380 - 2384 (1990)

Update date:2022-08-05

Topics:

Authors:

Adams Adams

Blake Blake

Broadhurst

Bushnell

Hassall Hassall

Hartmann

Keech Keech

Stratton

Thomas Thomas

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00171a011

a number of 4-demethoxyanthracyclines having hydroxylalkyl functions at the 9-position have previously been synthesized and shown to have potent antitumor activity. A series of carbamate derivatives of these (hydroxyalkyl)anthracyclines have now been prep

Full text of DOI:10.1021/jm00171a011

Products guided by the article

Product name:(7S,9S)-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-9-<1-(S)-<(phenylcarbamoyl)oxy>ethyl>-5,12-naphthacenedione

Cas No:91577-18-3

R&D Labs maybe for 91577-18-3

Xiamen Huasing Chemicals Co.Ltd.

Contact:0086-592-6228397

Address:NO.24, Xinglin North 2nd Road,Jimei district
Shanghai Longjin Metallic Material Co., Ltd.

website:http://www.shlongjin.cn/

Contact:021-56517503,56502257

Address:No.16, Lane 555, Chengyin Road, Shanghai
Hangzhou Gangjin Chemical Co.,Ltd.(expird)

Contact:+86-571-85109780

Address:707 Zhejiang Minhang Bldg., No.290 Zhongshan North Road, Hangzhou 310003, China
China Synchem Technology Co.,Ltd

website:http://www.cnsynchem.com

Contact:+86-0552-4929311

Address:No.217 Daqing Road
Valiant Fine Chemicals Co., Ltd.

Contact:+86 535 6101878/6374484

Address:11 Wuzhishan Rd.,YTETDZ,Yantai,264006,Shandong,China

Relevant to this article

Nucleophilic Aromatic Substitution in the Pyrrole Ring: Leaving Group Effect

Doi:10.1021/jo00195a040
(1984)
Organotin(IV) complexes of thiohydrazides and thiodiamines: synthesis, spectral and thermal studies

Doi:10.1016/j.saa.2006.01.040
(2006)
A concise and enantioselective approach to the total synthesis of (-)-lasubine I

Doi:10.1016/j.tetlet.2006.08.137
(2006)
A biocompatible surfactant with folded hydrophilic head group: Enhancing the stability of self-inclusion complexes of ferrocenyl in a β-cyclodextrin unit by bond rigidity

Doi:10.1021/ja064591q
(2006)
A Simple Preparation of Anhydrous Trifluoromethanesulfinate (Triflinate) Salts and Synthesis of Trifluoromethyl Sulfones (Triflones)

Doi:10.1055/s-1984-30826
(1984)
Tandem ring expansion of alkenyl benzocyclobutenol derivatives into substituted naphthols

Doi:10.1002/anie.200602428
(2006)

Article Doi