Synthesis and antitumor activity of 9-[(carbamoyloxy)alkyl]anthracyclines: A novel class of anthracycline derivatives

DOI: 10.1021/jm00171a011

Source and publish data:

Journal of Medicinal Chemistry p. 2380 - 2384 (1990)

Update date:2022-08-05

Topics:

Authors:

Adams Adams

Blake Blake

Broadhurst

Bushnell

Hassall Hassall

Hartmann

Keech Keech

Stratton

Thomas Thomas

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00171a011

a number of 4-demethoxyanthracyclines having hydroxylalkyl functions at the 9-position have previously been synthesized and shown to have potent antitumor activity. A series of carbamate derivatives of these (hydroxyalkyl)anthracyclines have now been prep

Full text of DOI:10.1021/jm00171a011

Products guided by the article

Product name:(7S,9S)-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-9-<1-(S)-<(phenylcarbamoyl)oxy>ethyl>-5,12-naphthacenedione

Cas No:91577-18-3

R&D Labs maybe for 91577-18-3

Shandong united-rising pharmaceutical cooperation.,ltd.

Contact:008653187965009

Address:171No., Jing5 Road, Shizhong District, Jinan, China
chemonlinephramacistdepot

Contact:86-607-68073220

Address:1 ave na road jiahua st
Ji'nan Orgachem Pharmaceutical Co.,Ltd

Contact:+86-531-82687810

Address:Jinan
Hubei Vanz Pharm Co.,Ltd

website:http://www.vanzpharm.com/en/index.html

Contact:86-27-84492310

Address:FANHU INDUSTRY PARK
SAGECHEM LIMITED

website:http://www.sagechem.com

Contact:+86-571-86818502

Address:Room C1301, New Youth Plaza, 8 Jia Shan Road, Hangzhou, China

Relevant to this article

Nucleophilic Aromatic Substitution in the Pyrrole Ring: Leaving Group Effect

Doi:10.1021/jo00195a040
(1984)
Organotin(IV) complexes of thiohydrazides and thiodiamines: synthesis, spectral and thermal studies

Doi:10.1016/j.saa.2006.01.040
(2006)
A concise and enantioselective approach to the total synthesis of (-)-lasubine I

Doi:10.1016/j.tetlet.2006.08.137
(2006)
A biocompatible surfactant with folded hydrophilic head group: Enhancing the stability of self-inclusion complexes of ferrocenyl in a β-cyclodextrin unit by bond rigidity

Doi:10.1021/ja064591q
(2006)
A Simple Preparation of Anhydrous Trifluoromethanesulfinate (Triflinate) Salts and Synthesis of Trifluoromethyl Sulfones (Triflones)

Doi:10.1055/s-1984-30826
(1984)
Tandem ring expansion of alkenyl benzocyclobutenol derivatives into substituted naphthols

Doi:10.1002/anie.200602428
(2006)

Article Doi