Synthesis and antitumor activity of 9-[(carbamoyloxy)alkyl]anthracyclines: A novel class of anthracycline derivatives

DOI: 10.1021/jm00171a011

Source and publish data:

Journal of Medicinal Chemistry p. 2380 - 2384 (1990)

Update date:2022-08-05

Topics:

Authors:

Adams Adams

Blake Blake

Broadhurst

Bushnell

Hassall Hassall

Hartmann

Keech Keech

Stratton

Thomas Thomas

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00171a011

a number of 4-demethoxyanthracyclines having hydroxylalkyl functions at the 9-position have previously been synthesized and shown to have potent antitumor activity. A series of carbamate derivatives of these (hydroxyalkyl)anthracyclines have now been prep

Full text of DOI:10.1021/jm00171a011

Products guided by the article

Product name:(7S,9S)-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-9-<1-(S)-<(phenylcarbamoyl)oxy>ethyl>-5,12-naphthacenedione

Cas No:91577-18-3

R&D Labs maybe for 91577-18-3

Taiwan Surfactant Corp.

Contact:886 2 2541 0022

Address:8 Fl., No. 11, Sec. 1, Chung Shan North Rd., Taipei, Taiwan R.O.C.
Hangzhou jls Flame Retardants Chemical Co.,Ltd

Contact:+86-571-87250387/87250386

Address:MOGANSHAN RODA 1418# SHANGCHENG INDUSTRIAL PARK
SPRING CHEMICAL INDUSTRY CO.,LTD

Contact:86-187-66672125

Address:linchi industry park.zouping
Taiwan Surfactant Corp.

Contact:886 2 2541 0022

Address:8 Fl., No. 11, Sec. 1, Chung Shan North Rd., Taipei, Taiwan R.O.C.
Shanghai Coupling Pharmaceutical R&D Co., Ltd.(expird)

Contact:+86 021 50106671

Address:403 Room No.4 Buiding, No. 526 Ruiqing Road, Shanghai Zhangjiang Hi-Tech Park

Relevant to this article

Nucleophilic Aromatic Substitution in the Pyrrole Ring: Leaving Group Effect

Doi:10.1021/jo00195a040
(1984)
Organotin(IV) complexes of thiohydrazides and thiodiamines: synthesis, spectral and thermal studies

Doi:10.1016/j.saa.2006.01.040
(2006)
A concise and enantioselective approach to the total synthesis of (-)-lasubine I

Doi:10.1016/j.tetlet.2006.08.137
(2006)
A biocompatible surfactant with folded hydrophilic head group: Enhancing the stability of self-inclusion complexes of ferrocenyl in a β-cyclodextrin unit by bond rigidity

Doi:10.1021/ja064591q
(2006)
A Simple Preparation of Anhydrous Trifluoromethanesulfinate (Triflinate) Salts and Synthesis of Trifluoromethyl Sulfones (Triflones)

Doi:10.1055/s-1984-30826
(1984)
Tandem ring expansion of alkenyl benzocyclobutenol derivatives into substituted naphthols

Doi:10.1002/anie.200602428
(2006)

Article Doi