Synthesis and antitumor activity of 9-[(carbamoyloxy)alkyl]anthracyclines: A novel class of anthracycline derivatives

DOI: 10.1021/jm00171a011

Source and publish data:

Journal of Medicinal Chemistry p. 2380 - 2384 (1990)

Update date:2022-08-05

Topics:

Authors:

Adams Adams

Blake Blake

Broadhurst

Bushnell

Hassall Hassall

Hartmann

Keech Keech

Stratton

Thomas Thomas

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Article abstract of DOI:10.1021/jm00171a011

a number of 4-demethoxyanthracyclines having hydroxylalkyl functions at the 9-position have previously been synthesized and shown to have potent antitumor activity. A series of carbamate derivatives of these (hydroxyalkyl)anthracyclines have now been prep

Full text of DOI:10.1021/jm00171a011

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