954
R. Singh, N.K. Kaushik / Spectrochimica Acta Part A 65 (2006) 950–954
Table 6
Anti-fungal screening data of the ligands and their tin complexes. (Inhibition %) (Conc. 25, 50, 100 ppm)
Compound
Rhizoctonia solanii
Sclerotium rolfsii
25
50
100
ED50
25
50
100
ED50
L1
37.91
33.33
54.50
57.18
72.36
67.35
66.66
88.78
74.60
42.62
34.28
18.24
29.33
36.19
64.86
54.29
78.82
63.30
39.48
50.76
(C6H5CH2)3Sn(L1)Cl
(p-ClC6H4CH2)2Sn(L1)Cl2
L2
25.25
48.66
62.36
43.62
63.28
64.88
78.52
82.43
68.88
51.26
28.19
1.50
36.82
30.21
43.28
63.28
68.92
78.92
54.34
40.66
(C6H5CH2)3Sn(L2)Cl
(p-ClC6H4CH2)2Sn(L2)Cl2
L3
55.70
38.33
61.80
63.56
66.98
70.77
79.26
78.23
78.88
21.21
34.29
11.47
(C6H5CH2)3Sn(L3)Cl
(p-ClC6H4CH2)2Sn(L4)Cl2
3.6. Anti-fungal studies
Acknowledgements
The results reported in table reveal that the tin complexes
with these ligands are much more active than the parent ligand
against the same microorganisms. With increase in concentra-
tion of the compounds there occurs increase in percentage of
inhibition. Higher concentration proves inhibitory for fungal
growth.
The authors thank Dr. R.L. Gupta and Bijul Lakshman
A, Divison of Agricultural Chemicals, Indian Agricultural
Research Institute (IARI), Pusa, New Delhi for the anti-fungal
studies of the compounds and University Scientific Instrumen-
tation Center (USIC), University of Delhi, India for TG/DTA
studies.
4. Conclusion
References
1
[1] M. Hoch, Appl. Geochem. 16 (2001) 719.
On the basis of elemental analysis, spectral (UV, IR, H
[2] E. Arkis, D. Balkose, Polym. Degrad. Stab. 88 (1) (2005) 46.
[3] L. Pellerito, L. Nagy, Coord. Chem. Rev. 626 (2001) 161.
[4] K. Fent, Sci. Total Environ. 185 (1996) 151.
[5] M. Ashfaq, M.I. Khan, M.K. Baloch, A. Malik, J. Org. Chem. 689 (1)
(2004) 238.
and 13C NMR) and thermal data; the following structures rep-
resenting coordination have been proposed for the complexes
synthesized:
[6] R. Jain, N.K. Kaushik, J. Therm. Anal. Chem. 49 (1997) 713.
[7] W.G. Luehr, F.M. Gordeev, D.V. Patel, Pharmacia & Upjohn Company,
USA, PCT Int. Appl., 2003.
(i) N-Thiohydrazide complexes
[8] A.G. Davies, Organotin Chemistry, second ed., Wiley-VCH, Weinheim,
2004, p. 383.
[9] P.M. Samuel, D. de Vos, D. Raveendra, J.A.R.P. Sarma, S. Roy, Bioorg.
Med. Chem. Lett. 12 (2002) 61.
[10] Y.L. Nene, P.N. Thapliyal, Fungicides in Plant Disease Control, Oxford &
IBH, New Delhi, 1997, p. 531.
[11] J.T. Trevors, Bull. Environ. Contam. Toxicol. 37 (1986) 18.
[12] K. Sisido, Y. Takeda, Z. Kinugawa, J. Am. Chem. Soc. 83 (1961) 538.
[13] V.Y. Kazakova, Y. Partovskii, Dokl. Akad. Nauk. S.S.S.R. 134 (1960) 824;
V.Y. Kazakova, Y. Partovskii, Chem. Abstr. 55 (1961) 8483a.
[14] K.A. Jensen, J. Prakt. Chem. 159 (1941) 189;
K.A. Jensen, Chem. Abstr. 37 (1941) 27182.
(ii) N-Thiodiamine complexes
[15] D.J. Bauer, Chem. Abstr. 65 (1996) 2224e;
D.J. Bauer, British Patent, 1026, 401 (Geo 7c, d) Welcome Foundation Ltd.
[16] N. Manav, N. Gandhi, N.K. Kaushik, J. Therm. Anal. Chem. 61 (2000)
127.
[17] K. Nakamoto, Infrared and Raman Spectra of Inorganic Coordination Com-
pounds, John Wiley, New York, 1978.
[18] D.J. Batyr, M.P. Starysh, V.N. Shafranskii, Y.Y. Kharitomov, Russ. J. Inorg.
Chem. 19 (1974) 1517.
[19] H.H. Horowitz, G. Metzger, Anal. Chem. 35 (10) (1963) 1464.
[20] B.R. Currel, in: R.F. Schwenker, P.D. Garn (Eds.), Thermal Analysis, vol.
2, Academic Press, New York, 1969, p. 1185.
[21] J. Zsako´, J. Phys. Chem. 72 (7) (1968) 2406.