ENANTIOSPECIFIC SYNTHESIS OF SWAINSONINE, (1S, 2R, 8R, 8aR)-1,2,8-TRIHYDROXYOCTAHYDROINDOLIZINE, FROM D-MANNOSE

DOI: 10.1016/S0040-4039(01)90059-0

Source and publish data:

Tetrahedron Letters p. 1853 - 1856 (1984)

Update date:2022-08-03

Topics:

Authors:

Fleet, G. W. J.

Gough, M. J.

Smith, P. W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(01)90059-0

An enantiospecific synthesis of swainsonine from D-mannose is described; the heterocyclic rings of swainsonine are constructed by two intramolecular reductive aminations caused by the catalytic hydrogenation of an azidoaldehyde with 5 equivalents of hydrogen.

Full text of DOI:10.1016/S0040-4039(01)90059-0

Products guided by the article

Product name:Methanesulfonic acid (3aS,4S,6R,7S,7aR)-4-benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-yl ester

Cas No:91652-75-4

R&D Labs maybe for 91652-75-4

Xi'an HO-SHINE Bio-Technology Co., Ltd

Contact:+86 (29) 8248-5435/18292020086

Address:No.6 Shiyuan Road Xian City Shaanxi Province, 710048 China
Shanghai ZaiQi Bio-Tech Co., Ltd.,

Contact:+86-21-5482 4098

Address:Bldg. No.7, No.201 MinYi Rd，Songjiang CaoHeJing High-Tech Park Shanghai 201516 P,R,China
Advanced Biotech

Contact:+1-973-357-0577

Address:10 Taft Rd.
JiangXi Hong Run Chemical Co., Ltd

Contact:+86-0791-88521351

Address:XingHuo industrial zone in YongXiu county
ANGCHEN BRIGHTCHEM CO., LTD

website:http://www.angchenchem.com

Contact:+86-510-88302099 82327577

Address:Rm. 404/405, Floor 4th, No. 983 FengXiang Road, Wuxi, China

Relevant to this article

Antitumor studies. Part 1: Design, synthesis, antitumor activity, and AutoDock study of 2-deoxo-2-phenyl-5-deazaflavins and 2-deoxo-2-phenylflavin-5-oxides as a new class of antitumor agents

Doi:10.1016/j.bmc.2006.09.063
(2007)
Synthesis and Antiviral/Antitumor Activities of Certain 3-Deazaguanine Nucleosides and Nucleotides

Doi:10.1021/jm00377a002
(1984)
Cyclization of 2-benzoylamino-N-methyl-thiobenzamides to 3-methyl-2-phenylquinazolin-4-thiones

Doi:10.1002/jhet.5570430521
(2006)
Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110α inhibitors

Doi:10.1016/j.bmc.2006.09.047
(2007)
Access to stereodefined trisubstituted alkenes via rhodium-catalyzed 1,4-addition of potassium trifluoro(organo)borates to Baylis-Hillman adducts

Doi:10.1002/adsc.200505336
(2006)
Efficient synthesis and host-guest properties of a new class of calix[6]azacryptands

Doi:10.1021/jo061616v
(2006)

Article Doi