SPIROKETALS: A TOTAL SYNTHESIS OF (+/-)-TALAROMYCIN B VIA A STEREOSELECTIVE CATION-OLEFIN CYCLISATION STEP

DOI: 10.1016/S0040-4039(01)90106-6

Source and publish data:

Tetrahedron Letters p. 2035 - 2038 (1984)

Update date:2022-08-05

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Authors:

Kay, I.Trevor

Bartholomew, David

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Article abstract of DOI:10.1016/S0040-4039(01)90106-6

The acid catalysed rearrangement of an acetal derived from 2-hydroxymethyl-3-butene-1-ol proceeding via an intramolecular cation-olefin cyclisation provides acces to a 4-hydroxytetrahydropyran and thence to (+/-)-talaromycin B.

Full text of DOI:10.1016/S0040-4039(01)90106-6

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