at each polyamide concentration. For linear peptides, duplicate
measurements weremade on asingle sensor chip. After subtraction
of the background response from the blank flowcell, the responses
were normalized by division by Rmax, the estimated response for
a 1 : 1 DNA–polyamide complex, given by eqn (2). RDNA is the
loading of the DNA, Mpept and MDNA are the molecular weights of
the polyamide and DNA respectively.
Acknowledgements
This work was supported by Cancer Research UK.
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