Chemistry Letters p. 803 - 806 (1993)
Update date:2022-08-03
Topics:
Yoshizawa, Hidenori
Otaka, Akira
Habashita, Hiromu
Fujii, Nobutaka
2-Quinolinylmethyl thioethers were efficiently cleaved to generate the corresponding symmetrical disulfides using the following systems; FeCl3/N,N-dimethylformamide (DMF)/H2O, FeCl3/ethanol (EtOH)/H2O, and CuCl2/DMF/H2O.The 2-quinolinylmethyl group was utilized as a thiol protecting group in the synthesis of a model peptide.
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