A NEW AND FACILE ROUTE TO SPIRO-KETAL SKELETON VIA HIGHLY STEREOSELECTIVE C-O BOND FORMATION BY INTRAMOLECULAR MICHAEL ADDITION TO α,β-UNSATURATED SULFOXIDES

Article abstract of DOI:10.1016/S0040-4039(01)81347-2

Diastereoisomerically pure (E)- and (Z)-2-methyl-1,6-dioxaspiro<4.5>-decane (insect pheromone) was efficiently prepared via a highly stereocontrolled intramolecular Michael addition of hydroxyl group to an unsaturated sulfoxide moiety during the crucial c