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of Tf2O for the benzylation of mesitylene (1 mmol) with benzyl
alcohol (1 mmol), however, the results did not show significant
benzylation of mesitylene. It seems that the excess amount of
Tf2O leads to an unwanted reaction with benzyl alcohol. Therefore,
using the same equivalents of Tf2O and Ph3PO is necessary for the
success of this type of FC benzylation.
In summary, TPPD is an extremely efficient promoter for the
FC-benzylation of a variety of arenes. The good yields, use of a
1:1 molar ratio of arene and benzyl alcohol, mild reaction condi-
tions, metal-free conditions, room temperature reactions,23 and
no formation of by-products such as DBE are the main advantages
of the described method.
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Acknowledgments
We thank Razi University for generous financial support of this
work and Mr. Mehdi Sheikh-Arabi for his constructive help.
Supplementary data
Supplementary data associated with this article can be found, in
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