Bioorganic and Medicinal Chemistry Letters p. 1466 - 1470 (2007)
Update date:2022-08-04
Topics:
Byeon, Seong Rim
Lee, Ji Hoon
Sohn, Ji-Hoon
Kim, Dong Chan
Shin, Kye Jung
Yoo, Kyung Ho
Mook-Jung, Inhee
Lee, Won Koo
Kim, Dong Jin
New bis-styrylpyridine and bis-styrylbenzene derivatives were designed and synthesized. These 34 compounds were evaluated by Aβ fibril formation inhibitory assay using thioflavin T as a dye (named ThT assay). Most of them showed excellent inhibitory activ
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