ACETALS OF LACTAMS AND ACID AMIDES: 42.* CYCLIZATION OF DIENAMINO ESTERS; DIENOAMINE NITRILES; AND ACYLAMIDINES TO PYRIDINE DERIVATIVES

Article abstract of DOI:10.1007/BF00508675

The reaction of derivatives of alkylidene(cycloalkylidene)cyanoacetic ester, -malonodinitrile , and -cyanoacetamide with dimethylformamide diethylacetal with subsequent cyclization of the resulting enamine systems gives derivatives of pyridine, 2-pyridine, and isoquinoline. 2-Amino-3-cyano-4-methylpyridine, which was synthesized by this method, was converted to a pyrido<1,2-a>pyrimidine derivative.