Total synthesis of (R,R,R)- and (S,S,S)-schweinfurthin F: Differences of bioactivity in the enantiomeric series

DOI: 10.1016/j.bmcl.2006.11.096

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 911 - 915 (2007)

Update date:2022-07-31

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Authors:

Mente, Nolan R.

Wiemer, Andrew J.

Neighbors, Jeffrey D.

Beutler, John A.

Hohl, Raymond J.

Wiemer, David F.

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Article abstract of DOI:10.1016/j.bmcl.2006.11.096

Total synthesis of the (R,R,R)- and (S,S,S)-enantiomers of the natural product schweinfurthin F has been completed. Comparisons of spectral data and optical rotations with those reported for the natural product, as well as a variety of bioassay data, allo

Full text of DOI:10.1016/j.bmcl.2006.11.096

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