A Synthesis of Optically Active 4-Diethoxyphosphinyl-3-(1-hydroxyethyl)-2-azetidinone: A Potential Precursor to (1-Aminoalkyl)-phosphonic Acid Derivatives

DOI: 10.1246/bcsj.60.645

Source and publish data:

Bulletin of the Chemical Society of Japan p. 645 - 648 (1987)

Update date:2022-07-29

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Authors:

Shiozaki, Masao

Masuko, Hidekazu

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Article abstract of DOI:10.1246/bcsj.60.645

Optically active 4-diethoxyphosphinyl-3-(1-hydroxyethyl)-2-azetidinone (8) was synthesized from (2R,3R)-N-diethoxyphosphinylmethyl-2,3-epoxybutyramide derivatives, and compound 8 was alternatively synthesized from (3R,4R)-4-acetoxy-3-<(R)-1-(t-butyldimeth

Full text of DOI:10.1246/bcsj.60.645

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Product name:(2S,3R)-N-(diethoxyphosphinylmethyl)-N-(4-methoxybenzyl)-2-bromo-3-hydroxybutyramide

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