A Convenient Synthesis of Hydroxyphthalides

DOI: 10.1039/c39840000819

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 819 - 820 (1984)

Update date:2022-08-04

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Authors:

Freskos, John

Cynkowski, Tadeusz

Swenton, John S.

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Article abstract of DOI:10.1039/c39840000819

The Diels-Alder reaction of in situ generated cyclohexa-1,3-dienes with methyl 4,4-diethoxybut-2-ynoate (1) followed by reverse Diels-Alder and hydrolysis affords substituted hydroxyphthalides in good yield.

Full text of DOI:10.1039/c39840000819

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