Palladium-Catalyzed Arylation of Unsymmetrical Olefins. Bidentate Phosphine Ligand Controlled Regioselectivity

Article abstract of DOI:10.1021/jo00039a011

The palladium-catalyzed arylation of several unsymmetrical olefins by aryl triflates in the presence of bidentate phosphine ligands is described.The use of these ligands increases the influence that electronic factors have in determining the regioselectivity of the reaction.The catalyst performances allow a revisiting of the scheme that describes the regioselectivity outcome in Heck-type reactions.Furthermore, a general mechanism for the palladium-catalyzed arylation of olefins is proposed.