
Tetrahedron Letters p. 4587 - 4590 (1984)
Update date:2022-09-26
Topics:
Stevens, R. V.
Albizati, K. F.
A 3-alkyl-5-chloroisoxazole synthesis is described based on the cycloaddition of nitrile oxides to 1,1-dichloroethylene, an inexpensive dipolarophile.Substitution of the chloride in these adducts by various nucleophiles is also described.
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Doi:10.1021/jo061929q
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(1985)