Synthesis of phytosphingosine using olefin cross-metathesis: a convenient access to chain-modified phytosphingosines from d-lyxose

DOI: 10.1016/j.tet.2007.03.047

Source and publish data:

Tetrahedron p. 4310 - 4318 (2007)

Update date:2022-08-02

Topics:

Authors:

Chang, Chi-We

Chen, Yeng-Nan

Adak, Avijit Kumar

Lin, Kun-Hsien

Tzou, Der-Lii M.

Lin, Chun-Cheng

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Article abstract of DOI:10.1016/j.tet.2007.03.047

This work establishes a general protocol for synthesizing phytosphingosines with various lengths of lipid chains. The synthetic strategy included the Wittig reaction and olefin cross-metathesis as key steps. Combining these two C-C bond formation methods

Full text of DOI:10.1016/j.tet.2007.03.047

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