Journal of the Chemical Society. Chemical communications p. 883 - 884 (1984)
Update date:2022-08-05
Topics: Experimental Esters Synthetic equivalent
Okano, Kohji
Morimoto, Toshiaki
Sekiya, Minoru
The introduction of a primary aminomethyl unit at the α position of esters can be achieved in high yield by the silyl trifluoromethanesulphonate-catalysed reaction of ketene silyl acetals (2) with N,N-bis(trimethylsilyl)methoxymethylamine (1).
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