Non-steroidal antiinflammatory agents. 1. Synthesis of 4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl alkanoic acids by the Wittig reaction of quinisatines

Article abstract of DOI:10.1002/jhet.5570210450

The Wittig reaction of quinisatines with 1-ethoxycarbonylethyliden- and ethoxycarbonylmethylenetriphenylphosphorane has been investigated. In both cases unusual reaction products were isolated in high yields and converted to potential antiinflammatory aci