Vitamin C in Organic Synthesis: Reaction with p-Hydroxybenzyl Alcohol Derivatives

DOI: 10.1021/jo00242a037

Source and publish data:

Journal of Organic Chemistry p. 1535 - 1540 (1988)

Update date:2022-08-04

Topics: Organic synthesis Reaction Experimental Vitamin C

Authors:

Poss, Andrew J.

Belter, Randolph K.

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Article abstract of DOI:10.1021/jo00242a037

The reaction of L-ascorbic acid (1) with p-hydroxybenzyl alcohol (9) yields 2-(p-hydroxybenzyl)-3-ketohexulosonic acid lactone (10).This reaction proceeds by the addition of the conjugate base of ascorbic acid to the protonated quinone methide derived fro

Full text of DOI:10.1021/jo00242a037

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