Synthesis of difluoromethylene-containing 1,2,4-oxadiazole compounds via the reaction of 5-(Difluoroiodomethyl)-3-phenyl-1,2,4-oxadiazole with unsaturated compounds initiated by sodium dithionite

Article abstract of DOI:10.1055/s-2007-983705

5-(Difluoroiodomethyl)-3-phenyl-1,2,4-oxadiazole, synthesized by the iodination of the corresponding zinc reagent of 5-(bromodifluoromethyl)-3- phenyl-1,2,4-oxadiazole, reacted with various unsaturated compounds, such as alkenes, alkynes, pent-4-en-1-ols,