Novel Substituent Orientation in Reimer-Tiemann Reactions of Pyrrole-2-carboxylates

DOI: 10.1021/jo00206a012

Source and publish data:

Journal of Organic Chemistry p. 790 - 792 (1985)

Update date:2022-08-04

Topics:

Authors:

Smith, Kevin M.

Bobe, Frank W.

Minnetian, Ohannes M.

Hope, Hakon

Yanuck, Michael D.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00206a012

Reimer-Tiemann formylation reactions (base/CHCl3) on 5-substituted pyrrole-2-carboxylates (1, 6, 8, 9, 11, and 13) afford 2-formylpyrroles (5, 7, 10, 12, and 14) in which the formyl group is situated in the position originally occupied by the carboxylate

Full text of DOI:10.1021/jo00206a012

Products guided by the article

Product name:1H-Pyrrole-2-carboxylic acid, 4-formyl-3-methyl-, phenylmethyl ester

Cas No:94781-43-8

R&D Labs maybe for 94781-43-8

Shanghai UCHEM Inc.

Contact:+86-21-56338808

Address:799 Dunhuang Road, Putuo
Xi'an Galaxy Chemicals CO., Ltd

Contact:86-29-89380370

Address:No.8, Gaoxin three road, Xi'an city.
Yancheng Smiling Imp & Exp Co., Ltd.

Contact:+86-515-83173586

Address:Rm1207, BLD#03, Phoenix Plaza, Juheng Road, Yancheng, Jiangsu, P.R. China
Shanghai Sunwise Chemical Co., Ltd

website:http://www.sunwisechem.com

Contact:86-021-33883180

Address:Room 10E, Building G, Westlink Center, No. 2337 Gudai Road, Minhang District, Shanghai, China PC: 201100
Chemieliva Pharmaceutical Co., Ltd.

website:http://www.chemieliva.com

Contact:+86-23-67770219

Address:99 Longhua Road, Yubei District, 401147, Chongqing, China Email: sales@chemieliva.com Tel:0086-23-67770219 Fax: 0086-23-67770220 Attn: Andy Huang

Relevant to this article

Improved synthesis of substituted 6,7-dihydroxy-4-quinazolineamines: Tandutinib, erlotinib and gefitinib

Doi:10.3390/11040286
(2006)
A Simple and Convenient Method for the Preparation of Ketomethylene Peptide Analogues

Doi:10.1021/jo00207a038
(1985)
Nucleophilicity vs. basicity in reactions of n-butyllithium and tert-butyllithium with tetramethylstannane

Doi:10.1021/om00123a008
(1985)
Doi:10.1246/bcsj.34.1257
(1961)
An efficient microwave-assisted synthesis of 3,5-unsubstituted 4-substituted-6-aryl-3,4-dihydropyridin-2(1H)-ones derivatives

Doi:10.1002/jhet.5570440414
(2007)
CDC25A-inhibitory RE derivatives bind to pocket adjacent to the catalytic site

Doi:10.1039/c3mb00003f
(2013)

Article Doi