Novel Substituent Orientation in Reimer-Tiemann Reactions of Pyrrole-2-carboxylates

DOI: 10.1021/jo00206a012

Source and publish data:

Journal of Organic Chemistry p. 790 - 792 (1985)

Update date:2022-08-04

Topics:

Authors:

Smith, Kevin M.

Bobe, Frank W.

Minnetian, Ohannes M.

Hope, Hakon

Yanuck, Michael D.

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Article abstract of DOI:10.1021/jo00206a012

Reimer-Tiemann formylation reactions (base/CHCl3) on 5-substituted pyrrole-2-carboxylates (1, 6, 8, 9, 11, and 13) afford 2-formylpyrroles (5, 7, 10, 12, and 14) in which the formyl group is situated in the position originally occupied by the carboxylate

Full text of DOI:10.1021/jo00206a012

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