Synthesis and interaction of 5-(substituted-phenyl)-3-methyl-6,7-dihydropyrazolo[4,3-e] [1,4]diazepin-8(7H)-ones with benzodiazepine receptors in rat cerebral cortex

DOI: 10.1021/jm50001a025

Source and publish data:

Journal of Medicinal Chemistry p. 683 - 685 (1985)

Update date:2022-08-04

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Authors:

Baraldi Baraldi

Manfredini

Periotto

Simoni Simoni

Guarneri

Borea Borea

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Article abstract of DOI:10.1021/jm50001a025

On the basis of the anxiolytic property of ripazepam, 1-ethyl-4,6-dihydro-3-methyl-8-phenylpyrazolo[4,3-e][1,4]- diazepin-5(1H)-one, a series of isomeric 5-(phenyl-substituted)pyrazolo[4,3-e][1,4]diazepin-8-ones 3a-f were prepared and tested for their abi

Full text of DOI:10.1021/jm50001a025

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