Synthesis and interaction of 5-(substituted-phenyl)-3-methyl-6,7-dihydropyrazolo[4,3-e] [1,4]diazepin-8(7H)-ones with benzodiazepine receptors in rat cerebral cortex

DOI: 10.1021/jm50001a025

Source and publish data:

Journal of Medicinal Chemistry p. 683 - 685 (1985)

Update date:2022-08-04

Topics:

Authors:

Baraldi Baraldi

Manfredini

Periotto

Simoni Simoni

Guarneri

Borea Borea

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm50001a025

On the basis of the anxiolytic property of ripazepam, 1-ethyl-4,6-dihydro-3-methyl-8-phenylpyrazolo[4,3-e][1,4]- diazepin-5(1H)-one, a series of isomeric 5-(phenyl-substituted)pyrazolo[4,3-e][1,4]diazepin-8-ones 3a-f were prepared and tested for their abi

Full text of DOI:10.1021/jm50001a025

Products guided by the article

Product name:1H-Pyrazole-3-carboxamide, N-(2-[1,1'-biphenyl]-4-yl-2-oxoethyl)-5-methyl-4-nitro-

Cas No:94993-72-3

R&D Labs maybe for 94993-72-3

Quhua Zhongxing Refrigeration Technology Co.,Ltd.

Contact:+86-5708886618

Address:318 Bulding 2, No.866 Quhua Rd.,Kecheng District
Sino-Japan Chemical Co., Ltd.

website:http://www.sjc.com.tw

Contact:(886) 2-2396-6223

Address:14Fl., No. 99. Sec. 2, Jen Ai Road
Changzhou BaoKang Pharmaceutical & Chemical Co., Ltd

Contact:(86) 519-88782201 88784080 88785278

Address:Henglin town, changzhou,Jiangsu
Weihao Chemtech (ChangZhou) Co., Ltd.(expird)

Contact:051989185693

Address:NO 217 huangshan Rd ,Changzhou
Guangxi Nanning Guangtai Agriculture Chemical Co.,Ltd

Contact:+86-771-2311266

Address:Room703,Building12, Software Park Phase II,NO.68,Keyuan Road,Nanning City,Guangxi,China

Relevant to this article

Selective amidation of 2,6-dihalogenopurines: Application to the synthesis of new 2,6,9-trisubstituted purines

Doi:10.1021/jo071196p
(2007)
Stereoselective synthesis of spiro-β-lactams using d-(+)-glucose derived chiral pool: remarkable influence of the torquoelectronic effect

Doi:10.1016/j.tet.2007.06.073
(2007)
Palladium acetate-catalyzed cyclization reaction of 2,3-allenoic acids in the presence of simple allenes: An efficient synthesis of 4-(1′-Bromoalk- 2′(Z)-en-2′-yl)furan-2(5H)-one derivatives and the synthetic application

Doi:10.1021/ja072790j
(2007)
Further optimization of the M₁PAM VU0453595: Discovery of novel heterobicyclic core motifs with improved CNS penetration

Doi:10.1016/j.bmcl.2016.04.083
(2016)
Doi:10.1021/ja00871a029
(1962)
A safe and selective method for reduction of 2-nitrophenylacetic acid systems to N-aryl hydroxamic acids using continuous flow hydrogenation

Doi:10.1016/j.tetlet.2017.01.008
(2017)

Article Doi