Synthesis and interaction of 5-(substituted-phenyl)-3-methyl-6,7-dihydropyrazolo[4,3-e] [1,4]diazepin-8(7H)-ones with benzodiazepine receptors in rat cerebral cortex

DOI: 10.1021/jm50001a025

Source and publish data:

Journal of Medicinal Chemistry p. 683 - 685 (1985)

Update date:2022-08-04

Topics:

Authors:

Baraldi Baraldi

Manfredini

Periotto

Simoni Simoni

Guarneri

Borea Borea

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm50001a025

On the basis of the anxiolytic property of ripazepam, 1-ethyl-4,6-dihydro-3-methyl-8-phenylpyrazolo[4,3-e][1,4]- diazepin-5(1H)-one, a series of isomeric 5-(phenyl-substituted)pyrazolo[4,3-e][1,4]diazepin-8-ones 3a-f were prepared and tested for their abi

Full text of DOI:10.1021/jm50001a025

Products guided by the article

Product name:1H-Pyrazole-3-carboxamide, N-(2-[1,1'-biphenyl]-4-yl-2-oxoethyl)-5-methyl-4-nitro-

Cas No:94993-72-3

R&D Labs maybe for 94993-72-3

Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

website:http://www.shydtec.com

Contact:86-21-57721279

Address:Science and Technology Park, Songjiang District, Shanghai, China
Chengdu Cogon Bio-tech Co., Ltd.

Contact:86-28-85171192

Address:NO.52.YongFeng Rd. Chengdu,610041,P.R.China.
Shenzhen JYMed Technology Co.,Ltd.

website:http://www.jymedtech.com

Contact:+86-755-26612112

Address:1#8,9/F, Biomedicine innovation Industrial Park, No.14, Jinhui Road, Pingshan Sistrict, Shenzhen, China
Anqing World Chemical Co., Ltd.

Contact:+86-556-5800026

Address:Daguan Economic Development Zone of circular economy industrial park Anqing City Anhui province
Shandong Hongxiang Zinc Co., Ltd

Contact:086-0311-66187879

Address:DaWang developing zone

Relevant to this article

Selective amidation of 2,6-dihalogenopurines: Application to the synthesis of new 2,6,9-trisubstituted purines

Doi:10.1021/jo071196p
(2007)
Stereoselective synthesis of spiro-β-lactams using d-(+)-glucose derived chiral pool: remarkable influence of the torquoelectronic effect

Doi:10.1016/j.tet.2007.06.073
(2007)
Palladium acetate-catalyzed cyclization reaction of 2,3-allenoic acids in the presence of simple allenes: An efficient synthesis of 4-(1′-Bromoalk- 2′(Z)-en-2′-yl)furan-2(5H)-one derivatives and the synthetic application

Doi:10.1021/ja072790j
(2007)
Further optimization of the M₁PAM VU0453595: Discovery of novel heterobicyclic core motifs with improved CNS penetration

Doi:10.1016/j.bmcl.2016.04.083
(2016)
Doi:10.1021/ja00871a029
(1962)
A safe and selective method for reduction of 2-nitrophenylacetic acid systems to N-aryl hydroxamic acids using continuous flow hydrogenation

Doi:10.1016/j.tetlet.2017.01.008
(2017)

Article Doi