REACTION OF 2-AMINOBENZOXAZOLES WITH COMPOUNDS WITH ACTIVATED MULTIPLE BONDS

Article abstract of DOI:10.1007/BF00505708

The reaction of 2-aminobenzoxazoles with activated alkenes of the acrylic acid type and its derivatives and methyl vinyl ketone proceeds in the presence of basic catalysts to give products of mono- and diaddition at the exocyclic nitrogen atom.The reaction of 5(6)-substituted 2-aminobenzoxazoles with esters of propyl and acetylenedicarboxylic acids in the absence of catalysts leads to the production of condensed 2-oxopyrimidines.The effect of substituents and the reaction conditions on the course of the process was investigated.