Bioorganic and Medicinal Chemistry Letters p. 1339 - 1344 (1996)
Update date:2022-08-02
Topics:
Iwanowicz, Edwin J.
Lau, Wan F.
Lin, James
Roberts, Daniel G. M.
Seiler, Steven M.
Substituted 5-amidine indoles were constructed based upon a computational analysis of putative modes of binding to thrombin utilizing coordinates from the crystal structure of BMS-183,507-α-thrombin complex. These analogs display competitive kinetics for
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