
Journal of the Chemical Society. Chemical communications p. 383 - 384 (1981)
Update date:2022-08-05
Topics:
Numazawa, Mitsuteru
Nagaoka, Masao
Tsuji, Masachika
Osawa, Yoshio
A novel synthesis of estriol 16-glucuronide, a major estrogen involved in human pregnancy, has been accomplished using the controlled stereospecific alkaline hydrolysis of 2,4,16α-tribromoestrone and the selective glucuronidation of its hydrolysed product as key reactions.
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