NEW SYNTHETIC METHOD OF (Z)-4-ALKENOIC ACIDS USING RING-OPENING REACTION OF (Z)-4-HEXENOLIDE WITH ORGANOCOPPER REAGENT

Article abstract of DOI:10.1246/cl.1984.1795

(Z)-4-Hexenolide reacted regioselectively with diorganocuprates to give (Z)-4-alkenoic acids in high yields.Synthetic utility was demonstrated by the convenient synthesis of cis-jasmone.