Regioselective Functionalization of Bicyclic Piperazinedione Bridgehead Carbanions

DOI: 10.1021/ja00348a042

Source and publish data:

Journal of the American Chemical Society p. 3214 - 3220 (1983)

Update date:2022-08-04

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Authors:

Williams, Robert M.

Dung, Jen-Sen

Josey, John

Armstrong, Robert W.

Meyers, Harold

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Article abstract of DOI:10.1021/ja00348a042

Generation of bridgehead carbanions of bicyclic piperazinediones 2 and 3 with LDA in THF at -78 deg C (kinetic conditions) followed by quenching with various electrophiles results in mixtures of the two monosubstitution products 12 and 13 with relatively

Full text of DOI:10.1021/ja00348a042

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