(S)-N--5-iodo-2-methoxybenzamide Hydrochloride, a New Selective Radioligand for Dopamine D-2 Receptors

DOI: 10.1021/jm00118a031

Source and publish data:

Journal of Medicinal Chemistry p. 2027 - 2033 (1988)

Update date:2022-08-04

Topics:

Authors:

Paulis, Tomas de

Janowsky, Aaron

Kessler, Robert M.

Clanton, Jeffrey A.

Smith, Howard E.

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Article abstract of DOI:10.1021/jm00118a031

From salicylic acid, the two enantiomers of N-<(1-ethyl-2-pyrrolidinyl)methyl>-5-iodo-2-methoxybenzamide (6b) were prepared in a five-step synthesis.With use of Heindel's triazene method for introduction of the radionuclide, the iodine-125-labeled substit

Full text of DOI:10.1021/jm00118a031

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