Journal of Organic Chemistry p. 4173 - 4182 (1985)
Update date:2022-09-26
Topics:
Gorthey, Lee Ann
Vairamani, Mariappandar
Djerassi, Carl
Circular dichroism and proton magnetic resonance spectroscopy were used in the conformational analysis of a series of β-heteroatom-substituted cyclohexanones.It was found that the axial population of the substituted ketone relative to that of the monosubstituted cyclohexanone is enhanced for the more highly electronegative substituents oxygen and fluorine and decreased for the less electronegative substituents chlorine, bromine, and sulfur.Possible mechanisms underlying this behavior, including electrostatic and dipole-dipole interactions as well as through-space and through-bond orbital interactions, are briefly discussed.
View MoreContact:410-273-7300; 800-221-3953
Address:4609 Richlynn Dr., PO Box 369, Belcamp, MD, 21017-0369, USA
Nanjing Chemical Material Corp.(NCMC)
website:http://www.njchemm.com
Contact:0086-25-83172879
Address:B12 Technology and Innovation Building, Nanjing Tech University, No.5 New Model Road
Huaian Double Win Chemicals Co.,Ltd.
Contact:+86-13511538872
Address:Blk 43,Greenland Century Town,Huaian District, Huaian City,Jiangsu Province,China
Weifang Jahwa Chemical Co.,Ltd
Contact:0086-536-8897731,8897730
Address:No.5166 East Dongfeng Street,Weifang,Shandong,China
Guangxi Nanning Guangtai Agriculture Chemical Co.,Ltd
Contact:+86-771-2311266
Address:Room703,Building12, Software Park Phase II,NO.68,Keyuan Road,Nanning City,Guangxi,China
Doi:10.1016/S0040-4039(02)02328-6
(2002)Doi:10.1246/cl.170363
(2017)Doi:10.1016/S0040-4039(00)61906-8
(1985)Doi:10.1021/jp964077e
(1997)Doi:10.1021/ac00291a005
(1985)Doi:10.1039/P29870000811
(1987)