COMPLETELY STEREOSELECTIVE SYNTHESIS OF ALL FOUR STEREOISOMERIC 1-CARBAMOYLOXY-1,3-ALKADIENES VIA ANTI-DIASTEREOSELECTIVE HOMOALDOL REACTION FROM ALDEHYDES AND A SINGLE CARBON-THREE-UNIT

Article abstract of DOI:10.1016/S0040-4039(00)61897-X

Lithiation of both (Z)- and (E)-3-trimethylsilyl-2-propenyl N,N-diisopropyl carbamate 2 affords the (2E)-lithium compound 3.Aluminium- or titanium-mediated addition to aldehydes 4 gives (1E)-(3R^*4S^*)-enol carbamates 7.A stereospecifi