Journal of Organic Chemistry p. 3669 - 3670 (1985)
Update date:2022-07-29
Topics:
Overman, Larry E.
Lin, Nan-Horng
(+)-Pumiliotoxin A (2), the parent alkaloid of the cardiac-active pumiliotoxin A class, can be prepared in 13 steps and 5percent overall yield from (S)-(-)-2-methyl-1-penten-3-ol (4).This enantioselective total synthesis establishes, for the first time, t
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