Amidine Protecting Groups for Oligonucleotide Synthesis

DOI: 10.1021/ja00268a052

Source and publish data:

Journal of the American Chemical Society p. 2040 - 2048 (1986)

Update date:2022-07-29

Topics:

Authors:

McBride, Lincoln J.

Kierzek, Ryszard

Beaucage, Serge L.

Caruthers, Marvin H.

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Article abstract of DOI:10.1021/ja00268a052

Amidines have been investigated for protection of deoxyadenosine, deoxycytidine, 5-methyldeoxycytidine, cytidine, and deoxyguanosine.These amidine-protected nucleosides and their 5'-bis(p-anisylphenyl)methyl derivatives were prepared in high yield (79-100

Full text of DOI:10.1021/ja00268a052

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