Journal of Organic Chemistry p. 46 - 50 (1986)
Update date:2022-08-04
Topics:
Denis, Jean-Noel
Greene, Andrew E.
Serra, A. Aarao
Luche, Marie-Jacqueline
An asymmetric epoxidation (70-80percent ee) and a highly regioselective epoxide cleavage have been used as the key reactions in the synthesis of the taxol side chain methyl ester (2; <*>95percent ee, 23percent overall yield from phenylacetylene.Transesterifications of 2 (in four steps) have been effected and are exemplified with (-)-isopinocampheol (8), 1,2;3,4-di-O-isopropylidene-D-galactopyranose (9), and methyl gibberellate (10).
View MoreXiamen XM-Innovation Chemical Co., Ltd
Contact:+86-592-3216205
Address:Unit Q, 11/F, No.1 Office Building, Wuyuan Bay Business Center, Huli District, Xiamen City, Fujian Province, P.R.C
Contact:+65 9658 0999
Address:26 Sin Ming Lane, Midview City, #05-118, Singapore 573971
Wuhan Silworld Chemical Co.,Ltd
website:http://www.silworldchemical.com
Contact:+86-27-85613400
Address:No.198 jiangjun Road, Wuhan,China 430033
Taizhou Shengxing Chempharm Co.,Ltd
Contact:+86-576-88516600
Address:Yantou Chemical Zone Jiaojiang Taizhou Zhejiang China
Synochem Ingredients Corp., Ltd.
Contact:+86-512-5636 2180
Address:Zhangjiagang Free Trade Zone
Doi:10.1021/jo01100a005
(1958)Doi:10.1039/b713244c
(2007)Doi:10.1016/S0040-4039(01)02244-4
(2002)Doi:10.1021/ol8004936
(2008)Doi:10.1016/S0040-4020(01)98562-X
(1963)Doi:10.1016/j.bmcl.2007.09.066
(2007)
