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acknowledgements
Financial support from the National Basic Research Program of China (973 Program)
(no. 2015CB856600), the National Natural Science Foundation of China (nos 21632001
and 21772002) and Peking University Health Science Center (no. BMU20160541) are
appreciated.
author contributions
J.L. and N.J. conceived and designed the experiments; J.L., X.Q. and C.Z. carried out
most of experiments; J.L., X.Q., X.L., J.W., J.P. and N.J. analysed data; J.L., X.Q., X.H., J.W.,
J.P., Y.L., Y.Z., Q.Q., S.S. and N.J. participated in discussion and co-wrote the paper; N.J.
directed the project.
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Competing interests
The authors declare no competing interests.
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additional information
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