CHEMOSELECTIVE REDUCTION OF CARBOXYLIC ACIDS INTO ALCOHOLS USING N,N-DIMETHYLCHLOROMETHYLENIMINIUM CHLORIDE AND SODIUM BOROHYDRIDE

DOI: 10.1246/cl.1983.835

Source and publish data:

Chemistry Letters p. 835 - 838 (1983)

Update date:2022-08-10

Topics:

Authors:

Fujisawa, Tamotsu

Mori, Toshiki

Sato, Toshio

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Article abstract of DOI:10.1246/cl.1983.835

A new method for the direct conversion of carboxylic acids to alcohols using N,N-dimethylchloromethyleniminium chloride and sodium borohydride was established.This method fulfills the chemoselective reduction of carboxylic acids with a functional moiety such as halide, ester, nitrile, and olefin.

Full text of DOI:10.1246/cl.1983.835

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