Stereocontrolled Lactonization Reactions via Palladium-Catalyzed 1,4-Addition to Conjugated Dienes

Article abstract of DOI:10.1021/jo00072a029

Stereocontrolled palladium(II)-catalyzed 1,4-chloro- and 1,4-acetoxylactonizations of conjugated cyclic dienes have been developed to give stereodefined fused lactones.The stereochemistry of the 1,4-acetoxylactonization was controlled by the ligand on the