A preparative scale reduction of alkyl disulfides with tributyl phosphine and water

Article abstract of DOI:10.1080/00397919908085777

A series of alkyl disulfides has been shown to be reduced by tributyl phosphine at room temperature. The resulting thiols were then acylated in the same pot and isolated in good yields. This sequence is convenient and is a practical option for the preparation of gram quantities of thiol or thioester from the corresponding disulfide.

Full text of DOI:10.1080/00397919908085777

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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A Preparative Scale Reduction
of Alkyl Disulfides with Tributyl
Phosphine and Water
Joshua T. Ayers a & Shelby R. Anderson a
a Department of Chemistry , Trinity College ,
Hartford, CT, 06106
Published online: 17 Sep 2007.
To cite this article: Joshua T. Ayers & Shelby R. Anderson (1999) A Preparative
Scale Reduction of Alkyl Disulfides with Tributyl Phosphine and Water, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 29:3, 351-358, DOI: 10.1080/00397919908085777
To link to this article: http://dx.doi.org/10.1080/00397919908085777
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