Tetrahedron Letters p. 2099 - 2102 (1997)
Update date:2022-08-28
Topics:
Nakajima, Noriyuki
Ubukata, Makoto
In order to establish a mild conversion method of primary amides to nitriles, various types of carboxamides were heated under Swern oxidation conditions, (COCl)2-DMSO and Et3N, as a dehydrating agent to obtain desired nitriles in 75-96% yields.
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