Volume Change on Complex Formation Between Anions and Cyclodextrins in Aqueous Solution

Article abstract of DOI:10.1007/BF00649488

Partial molal volume changes during complex formation between SCN(1-), I(1-), and ClO4(1-) and α- and β-cyclodextrin have been determined by two independent methods of measurements; one based on density measurement and subsequent calculation of apparent molal volumes, the other on differentiating the association constants with respect to pressure.Results from the two methods are in good agreement.Negative volume changes were observed for complex formation between the anions and α-cyclodextrin while zero or slightly positive values were observed for complex formation with β-cyclodextrin.The result is consistent with the idea that the anions do not become dehydrated as they form complexes with cyclodextrins.