Chiral α-Amino Ketones from the Friedel-Crafts Reaction of Protected Amino Acids

DOI: 10.1021/jo00324a057

Source and publish data:

Journal of Organic Chemistry p. 2431 - 2433 (1981)

Update date:2022-08-17

Topics:

Authors:

McClure, D. E.

Arison, B. H.

Jones, J. H.

Baldwin, J. J.

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Article abstract of DOI:10.1021/jo00324a057

The Friedel-Crafts reaction employing N-methoxycarbonyl-protected α-amino acids is described.This method yields chiral α-amino ketones which can be further used to prepare doubly chiral vicinal amino alcohols.

Full text of DOI:10.1021/jo00324a057

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