An enantioselective synthesis of the Williams glycine template

DOI: 10.1016/0957-4166(95)00076-2

Source and publish data:

Tetrahedron Asymmetry p. 801 - 806 (1995)

Update date:2022-08-25

Topics:

Authors:

Van Den Nieuwendijk

Warmerdam

Brussee Brussee

Van Der Gen

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Article abstract of DOI:10.1016/0957-4166(95)00076-2

The Williams glycine template for amino acid synthesis, benzyl (2R,3S)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate (1), was prepared in enantiomerically pure form in six steps from benzaldehyde in 48% overall yield. The initial chirality of the molecule wa

Full text of DOI:10.1016/0957-4166(95)00076-2

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