Simple and Efficient Copper-Catalyzed One-Pot Conversion of Aldehydes into Nitriles

DOI: 10.1055/s-1989-27285

Source and publish data:

Synthesis p. 451 - 452 (1989)

Update date:2022-08-31

Topics:

Authors:

Capdevielle, Patrice

Lavigne, Andre

Maumy, Michel

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Article abstract of DOI:10.1055/s-1989-27285

Aromatic, heterocyclic, and tertiary aliphatic nitriles are prepared from the corresponding aldehydes by the ammonium chloride/copper powder/oxygen system in pyridine.This new one-flask procedure affords very high to quantitative yields of pure nitriles.

Full text of DOI:10.1055/s-1989-27285

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