A simple and efficient 2N2O-Cu(II) complex as a catalyst for N-arylation of imidazoles in water

Article abstract of DOI:10.1002/aoc.3317

Four inexpensive and air- and moisture-stable 2N2O-Cu complexes were synthesized, one of which proved to exhibit good catalytic activity for the N-arylation of imidazoles in water. A variety of aryl iodides and aryl bromides underwent coupling with imidazoles promoted by the catalytic system with moderate to excellent yields.