Tetrahedron Letters p. 7781 - 7784 (1993)
Update date:2022-08-17
Topics:
Poch, Marta
A new and efficient enantioselective synthesis of Boc-α-amino acids has been developed. Starting from an enantiomerically enriched epoxy alcohol the sequence involves a regioselective nucleophilic epoxide opening by diphenylmethylamine (benzhydrilamine), hydrogenolysis/ protection of the amino group, and oxidation of the diol moiety.
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Doi:10.1080/00397919508010812
(1995)Doi:10.4067/s0717-97072015000300006
(2015)Doi:10.1021/jo01165a015
(1947)Doi:10.1039/b407712a
(2004)Doi:10.1055/s-0040-1706424
(2021)Doi:10.1039/b810127b
(2008)
