Ring Opening of N-Tosylhistamine with Di-t-butyl Pyrocarbonate: Synthesis of 1,2-Diamino-4-tosylaminobutane Dihydrochloride

DOI: 10.1039/c39850001133

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1133 - 1134 (1985)

Update date:2022-08-30

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Authors:

Altman, Janina

Shoef, Nurith

Wilchek, Meir

Warshawsky, Abraham

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Article abstract of DOI:10.1039/c39850001133

Bamberger ring-cleavage acylation of N-tosylhistamine with di-t-butyl pyrocarbonate in acetonitrile-aqueous potassium acetate leads to 3,4-bis(di-t-butoxycarbonylamino)but-3-enyl(tosyl)amine, which, after hydrogenation and treatm

Full text of DOI:10.1039/c39850001133

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